Iksgiza Lake is a lake located in Yukon-Koyukuk County, Alaska. It appears on the Kantishna River D-1 SE USGS 7.5-minute topographic quadrangle. The elevation at this location is approximately 329.63 feet (100.47 m) above sea level. The nearest populated place is Tutlut (historical), approximately 7.5 miles to the E.