Huslia River is a stream located in Yukon-Koyukuk County, Alaska. It appears on the Kateel River C-2 NE USGS 7.5-minute topographic quadrangle. The elevation at this location is approximately 155.18 feet (47.30 m) above sea level. The nearest populated place is Hussliakatna (historical), approximately 0.9 miles to the NW.