Mud Creek is a stream located in Yukon-Koyukuk County, Alaska. It appears on the Wiseman B-5 SE USGS 7.5-minute topographic quadrangle. The elevation at this location is approximately 1,135.95 feet (346.24 m) above sea level. The nearest populated place is Old Bettles (historical), approximately 33.0 miles to the SSE.