Mesquite Census Designated Place is a census located in Starr County, Texas. It appears on the Roma-Los Saenz East USGS 7.5-minute topographic quadrangle. The elevation at this location is approximately 185.12 feet (56.42 m) above sea level. The nearest populated place is Mesquite Number 2 Colonia, approximately 0.1 miles to the NNE.